1609646-99-2Relevant academic research and scientific papers
Application of 3-bromo-3-ethylazetidines and 3-ethylideneazetidines for the synthesis of functionalized azetidines
Stankovi?, Sonja,D'Hooghe, Matthias,Vanderhaegen, Tim,Abbaspour Tehrani, Kourosch,De Kimpe, Norbert
, p. 75 - 80 (2014/01/06)
The synthetic utility of 3-bromo-3-ethylazetidines has been demonstrated by the straightforward preparation of 3-alkoxy-, 3-aryloxy-, 3-acetoxy-, 3-hydroxy-, 3-cyano-, 3-carbamoyl- and 3-amino-3-ethylazetidines. In addition, 3-bromo-3-ethylazetidines have been successfully deployed as precursors for a convenient synthesis of 3-ethylideneazetidines, which served as starting materials for the preparation of novel functionalized azetidines and spirocyclic azetidine building blocks. Georg Thieme Verlag Stuttgart · New York.
