1609691-81-7Relevant articles and documents
Silyl imine electrophiles in enantioselective catalysis: A rosetta stone for peptide homologation, enabling diverse N-protected aryl glycines from aldehydes in three steps
Makley, Dawn M.,Johnston, Jeffrey N.
, p. 3146 - 3149 (2014)
We report that N-(trimethylsilyl)imines serve in the Bis(AMidine)-catalyzed addition of bromonitromethane with a high degree of enantioselection. This allows for the production of a range of protected α-bromo nitroalkane donors (including Fmoc) for use in