160977-89-9Relevant academic research and scientific papers
Kainic Acid as Conformationally Constrained Glutamic Acid Analog in Peptide Synthesis
Artuso, Frorinda,Sindona, Giovanni,Athanassopoulos, Constantinos,Stavropoulos, George,Papaioannou, Dionissios
, p. 9309 - 9312 (2007/10/02)
A synthetic protocol is described which allows the incorporation of the γ-amide (Kan) and the γ-benzyl ester and ether of kainic acid (Kai) into peptide chains as exemplified with the synthesis of the substance P (SP) analogs 5>-SP5-11, 5, Kan6>-SP5-11, 6>-SP6-11, 5, Kai(Bzl)11>-SP5-11 and 5, Kol(Bzl)11>-SP5-11.
Synthesis and NMR Studies of N-Substituted Derivatives of Kainic Acid Dimethyl Esters
Papaioannou, Dionissios,Sivas, Manolis,Kouvelas, Elias,Francis, George W.,Aksnes, Dagfinn W.
, p. 831 - 836 (2007/10/02)
Dimethyl kainate derivatives incorporating the amino protecting groups, 9-fluorenylmethoxycarbonyl (Fmoc), tert-butoxycarbonyl (Boc) and triphenylmethyl (trityl, Trt), have been synthesized from (-)-α-kainic acid (2S,3S,4S)-2-carboxy-4-(1-methylethenyl)-
