1610023-35-2

Upstream product

• 494846-26-3 (+)-trans-(1R,3R)-2,2-dimethyl-3-phenylcyclopropanecarboxylic acid 
• 50672-13-4 (±)-trans-2,2-dimethyl-3-phenylcyclopropanecarboxylic acid 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 61751-36-8 (±)-trans-ethyl 2,2-dimethyl-3-phenylcyclopropanecarboxylate 

Downstream Products

• 1557243-20-5 (1R,3R)-N-[5-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-2,2-dimethyl-3-phenylcyclopropanecarboxamide 

Relevant academic research and scientific papers

α7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREOF-I

The present invention relates to chemical compounds of formula (I), with the substituents as described in the specification, useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of α7 nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also neuropathic pain and inflammatory diseases.