50672-13-4

Usage

Uses

Used in Pharmaceutical Industry:
2,2-dimethyl-3-phenylcyclopropanecarboxylic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity may contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid is utilized as a building block for the creation of novel agrochemicals. Its structural features could be leveraged to design pesticides or herbicides with improved efficacy and selectivity.
Used in Materials Science:
2,2-dimethyl-3-phenylcyclopropanecarboxylic acid is employed as a precursor in the development of advanced materials. Its unique structural elements may be incorporated into polymers, coatings, or other materials to enhance their properties, such as strength, durability, or chemical resistance.
Further research and studies are essential to fully understand the properties and potential applications of 2,2-dimethyl-3-phenylcyclopropanecarboxylic acid, enabling its integration into various industries for innovative solutions.

Upstream product

• 61751-36-8 2,2-Dimethyl-3-phenyl-cyclopropan-carbonsaeure-⁽¹⁾-ethylester 
• 623-73-4 diazoacetic acid ethyl ester 
• 768-49-0 (2-methyl-1-propenyl)-benzene 
• 93085-88-2 (+/-)-trans-2,2-dimethyl-3-phenylcyclopropanecarboxamide 
• 105640-04-8 4,4-dimethyl-5-phenyldihydrofuran-2(3H)-one 
• 99647-67-3 2,2-dimethyl-3-phenyl-cyclopropanecarbonitrile 
• 61751-36-8 (±)-trans-ethyl 2,2-dimethyl-3-phenylcyclopropanecarboxylate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 4192-77-2 ethyl cinnamate 

Downstream Products

• 4489-17-2 (+/-)-2,2-dimethyl-3t-phenyl-cyclopropane-r-carbonyl chloride 
• 157240-02-3 methyl (1S,3S)-2,2-dimethyl-3-phenylcyclopropanecarboxylate 
• 494846-57-0 (-)-trans-(1S,3S)-2,2-dimethyl-3-phenylcyclopropanecarboxylic acid 
• 494846-26-3 (+)-trans-(1R,3R)-2,2-dimethyl-3-phenylcyclopropanecarboxylic acid 
• 1557243-20-5 (1R,3R)-N-[5-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]-2,2-dimethyl-3-phenylcyclopropanecarboxamide 
• 1610023-35-2 C₁₂H₁₃ClO 
• 78003-28-8 trans-2,2-Dimethyl-3-(4-brom-phenyl)-cyclopropan-carbonsaeure-⁽¹⁾ 
• 93085-88-2 (+/-)-2,2-dimethyl-3c-phenyl-cyclopropane-r-carboxylic acid amide 

Relevant academic research and scientific papers

ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREOF

Disclosed are compounds of Formula (IVA), or a salt thereof, and pharmaceutical formulations (pharmaceutical compositions) comprising those compounds, or a salt thereof: Formula (IVA), wherein "RIa", "RIb", "RIc", "RId", "RIe", are defined herein above, which compounds are believed suitable for use in positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR) receptors, for example, those found in the cerebral cortex and the hippocampus. Such compounds and pharmaceutical formulations are believed to be useful in treatment or management of neurodegenerative diseases, for example, Alzheimer's disease (AD), schizophrenia, and Parkinson's disease (PD), or movement disorders arising from use of certain medications used in the treatment or management of Parkinson's disease.

α7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREOF-I

The present invention relates to chemical compounds of formula (I), with the substituents as described in the specification, useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of α7 nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also neuropathic pain and inflammatory diseases.

N-(BENZIMIMDAZOL-2-YL)-CYCLOPROPANE CARBOXAMIDES AS LYSOPHOSPHATIDIC ACID ANTAGONISTS

The invention provides novel substituted cyclopropane carboxamide compounds according to Formula (I), their manufacture and use for the treatment of proliferative inflammatory diseases, such as cancer, fibrosis or arthritis.

Cyclopropyl aryl amide derivatives and uses thereof

Compounds of the formula: wherein Ar1, Ar2, R1 and R2 are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subject compounds.

A TANDEM MICHAEL REACTION-CYCLOALKYLATION UTILIZING 2-NITROPROPANE: A FACILE ROUTE TO THE ACID COMPONENT OF INSECTICIDAL PYRETHROIDS

Treatment of three representative β-substituted-α-cyanoacrylates (2) with 2-nitropropane and potassium carbonate in refluxing ethanol afforded stereoselectively cyclopropanoid precursors (4) to 3-substituted-2,2-dimethylcyclopropanecarboxylic acids (7).