1610343-51-5

Basic information

• Product Name: 1-(1',4-dimethyl-1-phenyl-1H,1'H-[3,4'-bipyrazol]-5-yl)-3-(1-oxo-2-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinolin-4-yl)urea
• Synonyms: 1-(1',4-dimethyl-1-phenyl-1H,1'H-[3,4'-bipyrazol]-5-yl)-3-(1-oxo-2-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinolin-4-yl)urea
• CAS NO: 1610343-51-5
• Molecular Weight: 521.502
• Mol File: 1610343-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1',4-dimethyl-1-phenyl-1H,1'H-[3,4'-bipyrazol]-5-yl)-3-(1-oxo-2-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinolin-4-yl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1',4-dimethyl-1-phenyl-1H,1'H-[3,4'-bipyrazol]-5-yl)-3-(1-oxo-2-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinolin-4-yl)urea(1610343-51-5)
• EPA Substance Registry System: 1-(1',4-dimethyl-1-phenyl-1H,1'H-[3,4'-bipyrazol]-5-yl)-3-(1-oxo-2-(2,2,2-trifluoroethyl)-1,2-dihydroisoquinolin-4-yl)urea(1610343-51-5)

Safety Data

• Hazardous Substances Data: 1610343-51-5(Hazardous Substances Data)

Upstream product

• 1610346-40-1 4-nitro-2-(2,2,2-trifluoroethyl)isoquinolin-1(2H)-one 
• 55404-29-0 4-nitroisoquinolin-1(2H)-one 
• 1414571-74-6 phenyl (1‘,4-dimethyl-1-phenyl-1H,1‘H-[3,4’-bipyrazol]-5-yl)carbamate 
• 1610346-42-3 4-amino-2-(2,2,2-trifluoroethyl)isoquinolin-1(2H)-one 
• 1414571-73-5 1′-4-dimethyl-1-phenyl-1H,1′H-[3,4′-bipyrazol]-5-amine 
• 1414571-72-4 2-methyl-3-(1-methyl-1H-pyrazol-4-yl)-3-oxopropanenitrile 
• 85290-80-8 ethyl 1-methylpyrazole-4-carboxylate 

Relevant articles and documents

BICYCLIC UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN

Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.