1610462-13-9

Basic information

• Product Name: (1S,2R)-5,8-dimethoxy-2-(3-chloro-4-methylphenyl)-1,2-dihydronaphthalen-1-ol
• CAS NO: 1610462-13-9
• Molecular Weight: 330.811
• Mol File: 1610462-13-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2R)-5,8-dimethoxy-2-(3-chloro-4-methylphenyl)-1,2-dihydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-5,8-dimethoxy-2-(3-chloro-4-methylphenyl)-1,2-dihydronaphthalen-1-ol(1610462-13-9)
• EPA Substance Registry System: (1S,2R)-5,8-dimethoxy-2-(3-chloro-4-methylphenyl)-1,2-dihydronaphthalen-1-ol(1610462-13-9)

Safety Data

• Hazardous Substances Data: 1610462-13-9(Hazardous Substances Data)

Upstream product

• 175883-63-3 B-(3-chloro-4-methylphenyl)boronic acid 
• 26002-73-3 1,4-dihydro-5,8-dimethoxy-1,4-epoxynaphthalene 

Relevant articles and documents

Nickel-catalyzed asymmetric ring opening of oxabenzonorbornadienes with arylboronic acids

A new, versatile, and highly efficient nickel-catalyzed asymmetric ring-opening (ARO) reaction of oxabenzonorbornadienes with a wide variety of arylboronic acids has been developed, yielding cis-2-aryl-1,2-dihydronaphthalen- 1-ols in high yields (up to 99%) with good to excellent enantioselectivities (up to 99% ee) under very mild conditions. The effects of various nickel precursors, chiral bidentate ligands, catalyst loadings, bases, solvents, and temperatures on the yield and enantioselectivity of the reaction were also investigated. A plausible mechanism was proposed to account for the formation of the corresponding cis-ring-opened products based on the X-ray structure of product 4b.