161064-06-8Relevant academic research and scientific papers
Anionic domino C-O-heterocyclization approach for the synthesis of 5-vinyl isoxazolines
Qazi, Naveed Ahmed,Singh, Parvinder Pal,Jan, Sumira,Kumar, H. M. Sampath
, p. 1449 - 1451 (2008/02/13)
5-Vinyl isoxazolines were isolated in high yields through domino nucleophilic addition-anionic C-O-heterocyclization, when allyl organometallics derived from trans-1,4-dihalobutene were reacted with nitrile oxides. Georg Thieme Verlag Stuttgart.
Conformationally restrained β-blocking oxime ethers. 2. Synthesis and β-adrenergic properties of diastereoisomeric anti and syn 2-(5'-(3'-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines
Balsamo,Breschi,Chiellini,Lucacchini,Macchia,Martinelli,Martini,Nardini,Orlandini,Romagnoli,Rossello
, p. 855 - 867 (2007/10/02)
The diastereoisomeric 2-(5'-(3'-aryl)isoxazolidinyl)ethaolamines 1c-h-4c-h were synthesized as analogs of the corresponding P-blocking isoxazolines unsubstituted on the aromatic ring 1a-4a, with the aim of checking the effects on the adrenergic properties
