1610681-07-6

Basic information

• Product Name: 1-(4-(dimethylamino)phenyl)-8-iodo-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one
• Synonyms: 1-(4-(dimethylamino)phenyl)-8-iodo-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one
• CAS NO: 1610681-07-6
• Molecular Weight: 444.275
• Mol File: 1610681-07-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-(dimethylamino)phenyl)-8-iodo-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(dimethylamino)phenyl)-8-iodo-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one(1610681-07-6)
• EPA Substance Registry System: 1-(4-(dimethylamino)phenyl)-8-iodo-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one(1610681-07-6)

Safety Data

• Hazardous Substances Data: 1610681-07-6(Hazardous Substances Data)

Upstream product

• 1203578-70-4 6-iodo-3-nitroquinolin-4-ol 
• 1610680-79-9 N'-(6-iodo-3-nitroquinolin-4-yl)-N,N-dimethylbenzene-1,4-diamine 
• 1610680-88-0 N-(4-(dimethylamino)phenyl)-6-iodoquinoline-3,4-diamine 
• 1610680-97-1 1-(4-(dimethylamino)phenyl)-8-iodo-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 74-88-4 methyl iodide 
• 1345447-25-7 4-chloro-6-iodo-3-nitroquinoline 
• 536-47-0 N,N-dimethyl-1,4-phenylenediamine sulfate 
• 1345447-21-3 5-iodo-2-((2-nitrovinyl)amino)benzoic acid 

Downstream Products

• 1610681-24-7 1-(4-(dimethylamino)phenyl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one 
• 1610681-17-8 1-(4-(dimethylamino)phenyl)-3-methyl-8-(pyridin-4-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one 

Relevant articles and documents

Establishment of a structure-activity relationship of 1 H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness

Compound NVP-BEZ235 (1) is a potent inhibitor of human phospoinositide-3- kinases and mammalian target of rapamycin (mTOR) that also showed high inhibitory potency against Trypanosoma brucei cultures. With an eye toward using 1 as a starting point for ant