1610802-74-8

Basic information

• Product Name: 4-(3-chloro-4-fluorophenyl)-1-methyl-1H-pyrazole
• Synonyms: 4-(3-chloro-4-fluorophenyl)-1-methyl-1H-pyrazole
• CAS NO: 1610802-74-8
• Molecular Weight: 210.638
• Mol File: 1610802-74-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-chloro-4-fluorophenyl)-1-methyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-chloro-4-fluorophenyl)-1-methyl-1H-pyrazole(1610802-74-8)
• EPA Substance Registry System: 4-(3-chloro-4-fluorophenyl)-1-methyl-1H-pyrazole(1610802-74-8)

Safety Data

• Hazardous Substances Data: 1610802-74-8(Hazardous Substances Data)

Upstream product

• 39806-90-1 4-iodo-1-methyl-1H-pyrazole 
• 144432-85-9 3-chloro-4-fluorophenylboronic acid 

Relevant articles and documents

Efficient synthesis of 4-substituted pyrazole via microwave-promoted Suzuki cross-coupling reaction

Pyrazoles and their derivatives are important heterocycles found in nature and present in numerous bioactive compounds. In contrast to 3 or 5-aryl pyrazole, the preparation of 4-aryl pyrazole is fairly rare. Utilizing microwave irradiation, the synthesis of 4-substituted-arylpyrazole via Suzuki cross-coupling has been developed with a wide range of substrates. The remarkable advantages of this method are mild reaction conditions, simple operation, high yield, and short reaction time. Product structures were identified by MS, 1H NMR, 13C NMR, and elemental analysis.