1610839-66-1

Basic information

• Product Name: (S)-methyl 1-(4-bromo-2-methylphenylcarbamoyl)-3,3-dimethyl-2-methylenecyclohexanecarboxylate
• Synonyms: (S)-methyl 1-(4-bromo-2-methylphenylcarbamoyl)-3,3-dimethyl-2-methylenecyclohexanecarboxylate
• CAS NO: 1610839-66-1
• Molecular Weight: 394.308
• Mol File: 1610839-66-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-methyl 1-(4-bromo-2-methylphenylcarbamoyl)-3,3-dimethyl-2-methylenecyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl 1-(4-bromo-2-methylphenylcarbamoyl)-3,3-dimethyl-2-methylenecyclohexanecarboxylate(1610839-66-1)
• EPA Substance Registry System: (S)-methyl 1-(4-bromo-2-methylphenylcarbamoyl)-3,3-dimethyl-2-methylenecyclohexanecarboxylate(1610839-66-1)

Safety Data

• Hazardous Substances Data: 1610839-66-1(Hazardous Substances Data)

Upstream product

• 5497-67-6 2,2-dimethyl-4-pentenal 
• 583-75-5 4-Bromo-2-methylaniline 
• 1610839-55-8 C₁₂H₁₈O₄ 
• 1610839-57-0 dimethyl 3,3-dimethyl-2-methylenecyclohexane-1,1-dicarboxylate 
• 1610839-59-2 dimethyl 2-(4,4-dimethylhex-5-ynyl)malonate 
• 122471-54-9 3,3-Dimethyl-6-iodo-1-hexyne 
• 680614-41-9 5-iodo-2,2-dimethylpentanal 
• 147377-61-5 4-(1,3-dioxolan-2-yl)-1-iodo-4-methylpentane 
• 104730-31-6 2-(4-hydroxy-1,1-dimethylbutyl)-1,3-dioxolane 
• 87802-43-5 4,4-dimethyl-5,5-(ethylenedioxy)-1-pentene 

Relevant articles and documents

Preparation of chiral building blocks for the enantioselective total synthesis of ent-kauranoids by the pig liver esterase-catalyzed asymmetric hydrolysis of a dialkyl malonate-type prochiral diester

The preparation of chiral building blocks, suitable for use in the enantioselective total synthesis of kauranoids and ent-kauranoids, is reported herein. The pig liver esterase-catalyzed asymmetric hydrolysis of dimethyl 3,3-dimethyl-2-methylenecyclohexane-1,2-dicarboxylate, a malonate-type prochiral diester, afforded the corresponding half-ester in 96% yield and with 99% enantiomeric excess. The absolute configuration of the half-ester was determined by X-ray crystallographic analysis of its derivative and its enantiodivergent transformations are also described herein.