1610849-05-2

Upstream product

• 1610849-30-3 2-[4-(2-biphenyl)piperazin-1-yl]-1-ethanol 
• 3300-51-4 p-Trifluoromethylbenzylamine 
• 1610849-32-5 3-[2-[4-(2-biphenyl)piperazin-1-yl]ethoxy]propanoic acid 
• 180698-18-4 1-([1,1'-biphenyl]-2-yl)piperazine 

Relevant academic research and scientific papers

Structural modifications of the serotonin 5-HT7 receptor agonist N -(4-cyanophenylmethyl)-4-(2-biphenyl)-1-piperazinehexanamide (LP-211) to improve in vitro microsomal stability: A case study

The 5-HT7 serotonin receptor is revealing a promising target for innovative therapeutic strategies of neurodevelopmental and neuropsychiatric disorders. Here, we report the synthesis of thirty long-chain arylpiperazine analogs of the selective

POLYCYCLIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF

The invention relates to a new class of compounds able to bind with high affinity and selectivity the 5-HT7 receptor. The invention also relates to the utilization of such compounds as medicaments useful in the treatment and prevention of 5-HT7 receptor relating disorders of the central nervous system. The invention also relates to the isotopically labeled compounds for use in vivo diagnosis or imaging of a 5-HT7 condition.