1610892-98-2Relevant academic research and scientific papers
Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase
Ceruso, Mariangela,Del Prete, Sonia,Alothman, Zeid,Osman, Sameh M.,Scozzafava, Andrea,Capasso, Clemente,Supuran, Claudiu T.
, p. 4006 - 4010 (2014)
New benzenesulfonamides incorporating GABA or N-α-acetyl-l-lysine scaffolds as well as guanidine functionalities as water solubilizing moieties were obtained, using 4-aminoethyl/methyl-benzenesulfonamide and metanilamide/sulfanilamide as zinc-binding moti
Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors
Ceruso, Mariangela,Antel, Sabrina,Scozzafava, Andrea,Supuran, Claudiu T.
, p. 205 - 211 (2016)
New ureido benzenesulfonamides incorporating a GABA moiety as a linker between the ureido and the sulfonamide functionalities were synthesized and their inhibition potency determined against both the predominant cytosolic (hCA I and II) and the transmembr
