1610941-65-5Relevant academic research and scientific papers
Palladium catalyzed direct C-2 arylation of indoles
Feng, Jie,Lu, Guoping,Lv, Meifang,Cai, Chun
, p. 28 - 31 (2014)
The synthesis and catalytic evaluation of palladium complexes containing NCN Pincer ligand is reported. The pincer palladium complexes as (pre)catalyst showed efficient catalytic activity for the C-H arylation of N-substituted indoles, allowing the synthesis of 2-arylindoles with moderate to good yields and excellent regioselectivities.
Substituent effect of diimino-palladium (II) pincer complexes on the catalysis of Sonogashira coupling reaction
Zhang, Jin-Hua,Li, Ping,Hu, Wen-Ping,Wang, Hong-Xing
, p. 107 - 112 (2015/06/02)
Three NCN diimine ligands 4-6 were synthesized after condensation of isophthalaldehydes 1-3 and anilines. Treatment of 4-6 with Pd2(dba)3 in toluene resulted in the corresponding PdII-NCN-But (7), PdII-NCN-H (8) and PdII-NCN-NO2 (9) pincer complexes, respectively with high yields. Palladium pincers 7-9 and their precursors 4-6 were fully characterized by elemental analysis, IR, 1H NMR and 13C NMR spectroscopy. The molecular structures of 7b and 9b were also determined by X-ray single crystal diffraction. Sonogashira coupling of phenyl acetylene and 3-nitrobenzene catalyzed by 7-9 show that 9 exhibits the highest catalytic activity, suggesting that the electron withdrawing groups at the position-4 of palladium atom in palladium pincers will enhance their catalytic activity.
