161099-08-7

Upstream product

• 107-30-2 chloromethyl methyl ether 
• 158780-52-0 phenylmethyl 2,3-O-(1-methylethylidene)-4-C-(prop-2-enyl)-α-D-lyxofuranoside 
• 158780-50-8 (3aR,4S,6S,6aS)-4-Allyl-6-benzyloxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid methyl ester 

Downstream Products

• 205864-59-1 4-((2R,3R,4R,5R)-5-Allyloxy-3,4-bis-benzyloxy-2-methoxymethoxymethyl-tetrahydro-furan-2-ylmethyl)-2,2-dimethyl-[1,3]dioxolane 
• 205864-61-5 (3R,4R,5R)-3,4-Bis-benzyloxy-5-(2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-5-methoxymethoxymethyl-dihydro-furan-2-one 
• 205864-55-7 (3aR,4R,6S,6aS)-6-Benzyloxy-4-(2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-4-methoxymethoxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole 
• 205864-58-0 (2R,3R,4R,5R)-2-Allyloxy-4-benzyloxy-5-(2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-5-methoxymethoxymethyl-tetrahydro-furan-3-ol 
• 205864-57-9 4-((2R,3R)-3-Benzyloxy-2-methoxymethoxymethyl-2,3-dihydro-furan-2-ylmethyl)-2,2-dimethyl-[1,3]dioxolane 

Relevant academic research and scientific papers

Towards the synthesis of the squalestatins/zaragozic acids: Synthesis of an advanced intermediate and introduction of the C-1 sidechain

A highly convergent synthesis of a squalestatin/zaragozic acid A C-4-decarboxydeoxy intermediate has been achieved. The key step involves the construction of the C-1-C-1′ bond by the addition of a fully functionalized C-1 sidechain anion (derived from iod

Synthetic Studies Towards the Squalestatins and Zaragozic Acids.

A synthesis of a model core system (18) of the squalestatins and zaragozic acids has been achieved from D-mannose.The key steps involve an Ireland-Claisen rearrangement of the allyl ester 5 and a stereoselective epoxidation of the furanoid glycal 12 with