161126-48-3

Basic information

• Product Name: 5-Isoxazolecarboxylicacid,4-(dimethoxymethyl)-3-phenyl-,methylester(9CI)
• Synonyms: 5-Isoxazolecarboxylicacid,4-(dimethoxymethyl)-3-phenyl-,methylester(9CI)
• CAS NO: 161126-48-3
• Molecular Formula: C14H15NO5
• Molecular Weight: 277.27
• Product Categories: ISOXAZOLE
• Mol File: 161126-48-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Isoxazolecarboxylicacid,4-(dimethoxymethyl)-3-phenyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolecarboxylicacid,4-(dimethoxymethyl)-3-phenyl-,methylester(9CI)(161126-48-3)
• EPA Substance Registry System: 5-Isoxazolecarboxylicacid,4-(dimethoxymethyl)-3-phenyl-,methylester(9CI)(161126-48-3)

Safety Data

• Hazardous Substances Data: 161126-48-3(Hazardous Substances Data)

Upstream product

• 1236189-14-2 (E)-methyl 4,4-dimethoxy-2-(phenylsulfinyl)but-2-enoate 
• 934-16-7 phenylhydroxamoyl chloride 
• 64677-38-9 methyl 4,4-dimethoxybut-2-ynoate 
• 698-16-8 benzohydroximoyl chloride 

Relevant articles and documents

SUBSTITUTED OXADIAZOLE DERIVATIVES AS S1P AGONISTS IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASES

Disclosed are compounds of Formula (I) [INSERT CHEMICAL STRUCTURE HERE] (I) or pharmaceutically acceptable salts thereof, wherein Q is [INSERT CHEMICAL STRUCTURE HERE] or [INSERT CHEMICAL STRUCTURE HERE]; R1 is alkyl or aryl, said aryl optionally substituted with one to five substituents independently selected from C1 to C6 alkyl, C1 to C4 haloalkyl, OR4, and/or halogen; and R2, R3, R4, and n are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.