934-16-7Relevant articles and documents
Decarboxylative Alkylation of Heteroarenes Using N-Hydroxybenzimidoyl Chloride Esters
Li, Xiaojuan,Zhang, Qiang,Zhang, Weigang,Wang, Yi,Pan, Yi
, p. 14360 - 14368 (2019)
Functionalized N-heteroarenes are highly desired motifs in medicinal chemistry and pharmaceutical industry. Minisci-type reactions usually require a protonated N-heteroarene for the alkyl radical to attack. This work describes a leaving-group-assisted redox-active ester to enable direct coupling of an amino acid with N-heteroarenes. The efficient and sustainable photoredox strategy provides rapid access to an alkylated heterocyclic manifold.
Terminal Alkyne-Assisted One-Pot Synthesis of Arylamidines: Carbon Source of the Amidine Group from Oxime Chlorides
Yi, Fengping,Sun, Qihui,Sun, Jing,Fu, Chao,Yi, Weiyin
supporting information, p. 6780 - 6787 (2019/06/14)
A terminal alkyne-assisted protocol for the one-pot formation of a diverse range of arylamidines from a novel cascade reaction of in situ generated nitrile oxides, sulfonyl azides, terminal alkynes, and water by [3 + 2] cycloaddition and ring opening sequ
Reaction between (Z)-Arylchlorooximes and α-Isocyanoacetamides: A procedure for the synthesis of Aryl-α-ketoamide amides
Giustiniano, Mariateresa,Mercalli, Valentina,Cassese, Hilde,Di Maro, Salvatore,Galli, Ubaldina,Novellino, Ettore,Tron, Gian Cesare
, p. 6006 - 6014 (2014/07/21)
(Z)-Arylchlorooximes and α-isocyanoacetamides undergo a smooth reaction to produce 1,3-oxazol-2-oxime derivatives in good yields. Opening of the oxazole ring and deoximation reaction give a facile access to aryl-α-ketoamide amides, a class of privileged s