1611494-91-7Relevant academic research and scientific papers
Chiral Aryliodine-Mediated Enantioselective Organocatalytic Spirocyclization: Synthesis of Spirofurooxindoles via Cascade Oxidative C-O and C-C Bond Formation
Cao, Yang,Zhang, Xiang,Lin, Guangyu,Zhang-Negrerie, Daisy,Du, Yunfei
, p. 5580 - 5583 (2016)
An enantioselective organocatalytic oxidative spirocyclization of alkyl 3-oxopentanedioate monoamide derivatives leading to the formation of diverse spirofurooxindoles with high enantioselectivity has been realized via chiral aryliodine-mediated cascade C-O and C-C bond formations. The reaction is postulated to proceed via oxidative C-O bond formation followed by oxidative C-C bond formation, with the latter being the enantioselectivity-determining step.
Catalytic Asymmetric Diamination of Styrenes
Mu?iz, Kilian,Barreiro, Laura,Romero, R. Martín,Martínez, Claudio
supporting information, p. 4354 - 4357 (2017/04/04)
An enantioselective catalytic vicinal diamination of styrenes is reported, which proceeds under entirely intermolecular reaction control. It relies on a chirally modified aryliodine(I) catalyst and proceeds within an iodine(I/III) manifold with conventional 3-chloroperbenzoic acid as a terminal oxidant. An environmentally benign solvent combination not only adds to the attractiveness of the process but also slows down the rate of the undesired background reaction. A total of 30 examples are presented, which consistently provide high enantiomeric excesses in the range 91-98%.
