161175-82-2Relevant academic research and scientific papers
Synthesis, molecular modelling and biological studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one derivatives as HIV-1 integrase inhibitors
Sirous, Hajar,Fassihi, Afshin,Brogi, Simone,Campiani, Giuseppe,Christ, Frauke,Debyser, Zeger,Gemma, Sandra,Butini, Stefania,Chemi, Giulia,Grillo, Alessandro,Zabihollahi, Rezvan,Aghasadeghi, Mohammad R.,Saghaie, Lotfollah,Memarian, Hamid R.
, p. 755 - 770 (2019/11/02)
Background: Despite the progress in the discovery of antiretroviral compounds for treating HIV-1 infection by targeting HIV integrase (IN), a promising and well-known drug target against HIV-1, there is a growing need to increase the armamentarium against
Synthesis of N-Substituted 3-Hydroxy-2-methyl-4-pyridones and -pyridonimines
Faerber, M.,Osiander, H.,Severin, T.
, p. 947 - 956 (2007/10/02)
Carbohydrates with 1,4-glycoside bonds like maltose, lactose, dextrin or strach react with primary amines as well as amino acids or proteins to give i.e. 3-hydroxy-2-methyl-4-pyridones 5 and 3-hydroxy-2-methyl-4-pyridonimines 7.A generally applicable synt
