16118-36-8

Basic information

• Product Name: H-DL-MET-OME HCL
• Synonyms: METHYL 2-AMINO-4-(METHYLTHIO)BUTANOATE HYDROCHLORIDE;DL-METHIONINE-OME HCL;DL-METHIONINE METHYL ESTER HCL;DL-METHIONINE METHYL ESTER HYDROCHLORIDE;H-DL-MET-OME HCL;TIMTEC-BB SBB003548;methyl DL-methionate hydrochloride;DL-methioninemethylesterHCl95+%
• CAS NO: 16118-36-8
• Molecular Formula: C₆H₁₄NO₂S*Cl
• Molecular Weight: 199.7
• EINECS: 240-285-0
• Mol File: 16118-36-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 277.6 °C at 760 mmHg
• Flash Point: 121.7 °C
• Appearance: /
• Vapor Pressure: 0.0388mmHg at 25°C
• Storage Temp.: −20°C
• Stability: Hygroscopic
• CAS DataBase Reference: H-DL-MET-OME HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-DL-MET-OME HCL(16118-36-8)
• EPA Substance Registry System: H-DL-MET-OME HCL(16118-36-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 16118-36-8(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

InChI:InChI=1/C6H13NO2S.ClH/c1-9-6(8)5(7)3-4-10-2;/h5H,3-4,7H2,1-2H3;1H/t5-;/m0./s1

Upstream product

• 10332-17-9 DL-methionine methyl ester 
• 67-56-1 methanol 
• 59-51-8 DL-methionine 

Downstream Products

• 62605-38-3 N-[N-(4-methoxy-benzyloxycarbonyl)-methionyl]-glycine 
• 207519-38-8 Fe(C₂₁H₂₆N₂O₄S)(CO)3 
• 145401-87-2 (R)-α-methylbenzylcarbamoyl-DL-methionine methyl ester 
• 1370228-80-0 (RS)-methyl 2-((N-(tert-butoxycarbonyl)-N-(3-phenoxybenzyl)sulfamoyl)amino)-4-(methylthio)butanoate 
• 108329-67-5 N-(tert-Butyloxycarbonyl)-L-tyrosyl-D-methionine 
• 180976-95-8 N-Boc-4-amino-3-methylbenzoyl methionine methyl ester 
• 180863-46-1 N-(1(S)-carbomethoxy-3-methylthiopropyl)3-chloromethylbenzamide 
• 180976-99-2 N-BOC-4-amino-3-methoxybenzoyl methionine methyl ester 
• 180863-61-0 N-(4-N-Boc-aminobenzoyl)-methionine methyl ester 

Relevant articles and documents

Adducts of rhodium(II) tetraacylates with methionine and its derivatives: 1H and 13C nuclear magnetic resonance spectroscopy and chiral recognition

Complexation of rhodium(II) dimeric tetraacylates: tetraacetate Rh 2AcO4, tetratrifluoroacetate Rh2TFA4 , and (S)-Mosher's acid salt Rh2MTPA4 with both enantiomerically pure and racemic met

Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives

Phosphine-catalyzed regiodivergent enantioselective C-2- and C-4-selective γ-additions of oxazolones to 2,3-butadienoates have been developed. The C-4-selective γ-addition of oxazolones occurred in a highly enantioselective manner when 2-aryl-4-alkyloxazol-5-(4H)-ones were employed as pronucleophiles. With the employment of 2-alkyl-4-aryloxazol-5-(4H)-ones as the donor, C-2-selective γ-addition of oxazolones took place in a highly enantioselective manner. The C-4-selective adducts provided rapid access to optically enriched α,α-disubstituted α-amino acid derivatives, and the C-2-selective products led to facile synthesis of chiral N,O-acetals and γ-lactols. Theoretical studies via DFT calculations suggested that the origin of the observed regioselectivity was due to the distortion energy that resulted from the interaction between the nucleophilic oxazolide and the electrophilic phosphonium intermediate.

Structural diversity-guided convenient construction of functionalized polysubstituted butenolides and lactam derivatives

A molecular diversity-oriented convenient access to multi-substituted butenolides and lactam scaffolds via four different methods from various phenylacetic acid derivatives is described. The target molecules have been identified on the basis of analytical spectra data, and are useful synthons in the fields of medicine and agrochemicals.