1612143-72-2Relevant academic research and scientific papers
A new polyketide from the mangrove endophytic fungus penicillium sp. sk14JW2P
Huang, Xi-Shan,Yang, Bin,Sun, Xue-Feng,Xia, Guo-Ping,Liu, Ya-Yue,Ma, Lin,She, Zhi-Gang
, p. 664 - 668 (2014)
Two polyketides were isolated from the mangrove endophytic fungus, Penicillium sp. sk14JW2P, and one derivative with a modified structure. The structures were elucidated by spectroscopic analyses, the structure of the compound 1 was further confirmed by single-crystal X-ray diffraction, and its absolute configuration was determined. Compound 1 and 2 showed acetylcholinesterase (AchE) inhibitory activities with IC50 values of 12±0.3 and 79±2 nM, respectively. Copyright
