1612156-05-4

Basic information

• Product Name: tert-butyl 4-(3-(1H-pyrazol-5-yl)phenyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-(3-(1H-pyrazol-5-yl)phenyl)piperidine-1-carboxylate
• CAS NO: 1612156-05-4
• Molecular Weight: 327.426
• Mol File: 1612156-05-4.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(3-(1H-pyrazol-5-yl)phenyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(3-(1H-pyrazol-5-yl)phenyl)piperidine-1-carboxylate(1612156-05-4)
• EPA Substance Registry System: tert-butyl 4-(3-(1H-pyrazol-5-yl)phenyl)piperidine-1-carboxylate(1612156-05-4)

Safety Data

• Hazardous Substances Data: 1612156-05-4(Hazardous Substances Data)

Upstream product

• 149739-65-1 5-(3-bromophenyl)-1H-pyrazole 
• 180695-79-8 tert-butyl 4-bromo-1-piperidinecarboxylate 

Relevant articles and documents

Reductive cross-coupling of nonaromatic, heterocyclic bromides with aryl and heteroaryl bromides

Reductive cross-coupling allows the direct C-C bond formation between two organic halides without the need for preformation of an organometallic reagent. A method has been developed for the reductive cross-coupling of nonaromatic, heterocyclic bromides with aryl or heteroaryl bromides. The developed conditions use an air-stable Ni(II) source in the presence of a diamine ligand and a metal reductant to allow late-stage incorporation of saturated heterocyclic rings onto aryl halides in a functional-group tolerant manner.