1612233-55-2

Upstream product

• 1612233-45-0 (S)-7-((tert-butyldimethylsilyl)oxy)-4-methylhept-2-yn-1-yl ethyl carbonate 
• 1612233-44-9 (S)-7-((tert-butyldimethylsilyl)oxy)-4-methylhept-2-yn-1-ol 
• 1612233-43-8 (S)-tert-butyl((6,6-dibromo-4-methylhex-5-en-1-yl)oxy)dimethylsilane 
• 529494-83-5 (S)-5-((tert-butyldimethylsilyl)oxy)-2-methylpentanal 
• 618096-59-6 (S)-5-((tert-butyldimethylsilyl)oxy)-2-methylpentan-1-ol 
• 618096-58-5 (S)-5-((tert-butyldimethylsilyl)oxy)-N-((1R,2R)-1-hydroxy-1-phenylpropan-2-yl)-N,2-dimethylpentanamide 
• 67-56-1 methanol 
• 1612233-53-0 (S)-5-(4-bromo-2-(phenylthio)oxazol-5-yl)-4-methylhepta-5,6-dienal 
• 1612233-51-8 (S)-5-(4-bromo-2-(phenylthio)oxazol-5-yl)-4-methylhepta-5,6-dien-1-ol 
• 1612233-49-4 (S)-4-bromo-5-(7-((tert-butyldimethylsilyl)oxy)-4-methylhepta-1,2-dien-3-yl)-2-(phenylthio)oxazole 
• 1612233-46-1 (S)-tert-butyldimethyl((4-methyl-7-(tributylstannyl)hept-5-yn-1-yl)oxy)silane 

Downstream Products

• 1612233-60-9 (S)-7-(4-bromo-2-(phenylthio)oxazol-5-yl)-6-methyl-1-methylene-5,6-dihydro-1H-inden-2(4H)-one 
• 1612233-57-4 (S)-7-(4-bromo-2-(phenylthio)oxazol-5-yl)-6-methyl-5,6-dihydro-1H-inden-2(4H)-one 

Relevant academic research and scientific papers

Total synthesis of (+)-ileabethoxazole via an iron-mediated pauson-khand [2 + 2 + 1] carbocyclization

Studies describe the total synthesis of (+)-ileabethoxazole (1) using a Stille cross-coupling reaction of propargylic stannanes with 5-iodo-1,3-oxazoles to produce 1,1-disubstituted allenes (11). An iron-mediated [2 + 2 + 1] carbocyclization yields a novel cyclopentenone for elaboration to 1. Site-selective palladium insertion reactions allow for regiocontrolled substitutions of the heterocycle. Asymmetric copper hydride reductions are examined, and strategies for the formation of the central aromatic ring are discussed.