1612262-35-7Relevant academic research and scientific papers
A chemical "hub" for absolute quantification of a targeted protein: Orthogonal integration of elemental and molecular mass spectrometry
Yan, Xiaowen,Li, Zhaoxin,Liang, Yong,Yang, Limin,Zhang, Bo,Wang, Qiuquan
, p. 6578 - 6581 (2014)
A novel element-tagged activity-based photo-cleavable biotinylated chemical "Hub" was designed and synthesized to orthogonally integrate ICP-MS and ESI-MS for absolute targeted-protein quantification. This tetrafunctional chemical "hub" allowed us to quantify a targeted protein using species-unspecific isotope dilution ICP-MS and to know which protein is being quantified using ESI-IT-MS at the same time. This journal is the Partner Organisations 2014.
