161266-92-8

Basic information

• Product Name: (R)-Cyclopent-2-enyl-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester
• Synonyms: (R)-Cyclopent-2-enyl-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester
• CAS NO: 161266-92-8
• Molecular Weight: 340.506
• Mol File: 161266-92-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-Cyclopent-2-enyl-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-Cyclopent-2-enyl-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester(161266-92-8)
• EPA Substance Registry System: (R)-Cyclopent-2-enyl-acetic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester(161266-92-8)

Safety Data

• Hazardous Substances Data: 161266-92-8(Hazardous Substances Data)

Downstream Products

• 696-67-3 (-)-(R)-cyclopent-2-en-1-yl-acetic acid 
• 65253-04-5 (-)-8-phenylmenthol 

Relevant articles and documents

A simple preparation of (R)-(2-cyclopentenyl)acetic acid and (R)-(2-cyclohexenyl)acetic acid using β-diastereoselective radical cyclization in the presence of Lewis acid

The alkenyl radical generated from (-)-8-phenylmenthyl 7-iodo-2,6-heptadienoate smoothly cyclized to afford (R)-(2-cyclopentenyl)acetate with 88% de in 90% yield. (R)-(2-Cyclohexenyl)acetate was also obtained with 84% de in 72% yield under the same conditions. The presence of Lewis acid is essential for high diastereoselectivity and chemical yield.