1612798-72-7Relevant academic research and scientific papers
Copper-catalyzed [18F]fluorination of (Mesityl)(aryl)iodonium salts
Ichiishi, Naoko,Brooks, Allen F.,Topczewski, Joseph J.,Rodnick, Melissa E.,Sanford, Melanie S.,Scott, Peter J.H.
supporting information, p. 3224 - 3227 (2014/07/08)
A practical, rapid, and highly regioselective Cu-catalyzed radiofluorination of (mesityl)(aryl)iodonium salts is described. This protocol utilizes [18F]KF to access 18F-labeled electron-rich, -neutral, and -deficient aryl fluorides under a single set of mild conditions. This methodology is applied to the synthesis of protected versions of two important radiotracers: 4-[18F]fluorophenylalanine and 6-[ 18F]fluoroDOPA.
