1612872-79-3Relevant academic research and scientific papers
RuHCl(CO)(PPh3)3-Catalyzed Direct Amidation of Arene C-H Bond with Azides
Xiao, Xinsheng,Jia, Guokai,Liu, Fang,Ou, Guangchuan,Xie, Ying
, p. 13811 - 13820 (2018/11/23)
We first report the direct ortho C-H amidation of arenes with azides by using a novel and inexpensive RuHCl(CO)(PPh3)3 catalyst. The reaction proceeds efficiently in high yield over a broad range of substrates without requirement of any additional silver salt or additive.
Ruthenium-catalyzed C7 amidation of indoline C-H bonds with sulfonyl azides
Pan, Changduo,Abdukader, Ablimit,Han, Jie,Cheng, Yixiang,Zhu, Chengjian
, p. 3606 - 3609 (2014/04/03)
A ruthenium-catalyzed direct C7 amidation of indoline C-H bonds with sulfonyl azides was developed. This procedure allows the synthesis of a variety of 7-amino-substituted indolines, which are useful in pharmaceutical. The good functional tolerances, as well as the mild conditions, are prominent feature of this method.
