161314-85-8

Basic information

• Product Name: D-Leucine, N-[(4-methoxyphenyl)sulfonyl]-
• CAS NO: 161314-85-8
• Molecular Formula: C13H19NO5S
• Molecular Weight: 301.364
• Mol File: 161314-85-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: D-Leucine, N-[(4-methoxyphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: D-Leucine, N-[(4-methoxyphenyl)sulfonyl]-(161314-85-8)
• EPA Substance Registry System: D-Leucine, N-[(4-methoxyphenyl)sulfonyl]-(161314-85-8)

Safety Data

• Hazardous Substances Data: 161314-85-8(Hazardous Substances Data)

Upstream product

• 328-38-1 (R)-leucine 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 

Downstream Products

• 161314-84-7 2(R)-[[4methoxybenzenesulfonyl](benzyl)amino]-4-methylpentanoic acid 
• 208663-26-7 N-hydroxy-2(R)-{[(4-methoxyphenyl)sulfonyl]-[benzyl]amino}-4-methylpentanamide 
• 161314-86-9 t-butyl 2(R)-[[4-methoxybenzenesulfonyl](benzyl)amino]-4-methylpentanoate 
• 161314-83-6 t-butyl 2(R)-[[4-methoxybenzenesulfonyl](3-picolyl)-amino]-4-methylpentanoate 
• 1026556-88-6 (R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-4-methyl-pentanoic acid tert-butoxy-amide 
• 1026045-87-3 (R)-2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-4-methyl-pentanoic acid tert-butoxy-amide 
• 161314-81-4 t-butyl 2(R)-[[4-methoxybenzenesulfonyl]amino]-4-methylpentanoate 

Relevant articles and documents

Highly enantioselective aza Morita-Baylis-Hillman reaction catalyzed by bifunctional β-isocupreidine derivatives

The aza-MBH reaction of imines 1 and β-naphthyl acrylate 2 in the presence of C-6′ modified β-isocupreidine derivative 1c (0.1 equiv) and β-naphthol 5 (0.1 equiv) afforded the corresponding (3S)-aza-MBH adducts 4 in high yield and excellent enantiomeric excess. These catalytic conditions allowed the aliphatic imines to be employed for the first time as electrophilic partners of the aza-MBH reaction. The coexistence of two H-bond donors with different acidic strengths was found to be crucial for the observed high enantioselectivity. Copyright