161327-24-8

Basic information

• Product Name: 2-bromo-4-(diethylamino) benzaldehyde
• Synonyms: 2-bromo-4-(diethylamino) benzaldehyde
• CAS NO: 161327-24-8
• Molecular Weight: 256.142
• Mol File: 161327-24-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-bromo-4-(diethylamino) benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-4-(diethylamino) benzaldehyde(161327-24-8)
• EPA Substance Registry System: 2-bromo-4-(diethylamino) benzaldehyde(161327-24-8)

Safety Data

• Hazardous Substances Data: 161327-24-8(Hazardous Substances Data)

Upstream product

• 621-38-5 3-bromoacetanilide 
• 59142-68-6 2-bromo-4-fluorobenzaldehyde 
• 109-89-7 diethylamine 
• 398151-69-4 3-Bromo-N-ethylaniline 
• 53142-19-1 3-bromo-bisethyl-aminobenzene 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 13482-21-8 N-(6-(diethylamino)-9-phenyl-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride 
• 1608130-71-7 4-(diethylamino)-2-(3-(diethylamino)phenoxy)benzaldehyde 

Relevant articles and documents

Hydrogen-bonding-induced bathochromic effect of Si-coumarin and its use in monitoring adipogenic differentiation

Introduction of a heteroatom into a fluorophore was carried out for coumarin through a replacement of its bridging oxygen atom with a silicon atom. The maximum-emission wavelength of Si-coumarin (SiC B) bathochromically shifted from 426 nm in cyclohexane to 626 nm in water. The adipogenic differentiation processes in mesenchymal stem cells were monitored using SiC B.

A class of silicon-substituted coumarin derivatives, and synthesis method thereof

The invention discloses a class of silicon-substituted coumarin derivatives, which have a structure represented by a formula I, wherein R is a nitrogen methyl group, a nitrogen ethyl group, a nitrogenhydrogen ethyl group, a nitrogen four-membered ring, a nitrogen ethyl five-membered ring or a nitrogen ethyl six-membered ring. According to the preparation, aniline is subjected to a formylation reaction by using a corresponding aromatic amine as a starting raw material and using phosphorus oxychloride and DMF as reaction reagents; the Ylide reaction of the aldehyde group is performed by using n-butyl lithium as a reaction reagent and using anhydrous THF as a solvent; a lithiation reaction is performed by using n-butyl lithium as reaction reagent to obtain a dimethyl silicon substituted intermediate; and finally diene is subjected to a double decomposition reaction under the catalysis of a Grubbs II catalyst to achieve the intramolecular ring closure, and oxidation is performed with selenium dioxide to obtain the final product. According to the present invention, a class of the novel silicon-substituted coumarin derivatives are synthesized, are sensitive to environmental polarity, and can be used for monitoring the activity of cells in vivo.

NEAR-INFRARED FLUORESCENT DYES AND USES THEREOF

The invention relates to a near-infrared fluorescent dye and use thereof, and particularly relates to compounds represented by following Formulae A, B and C, wherein each group in the Formulae is described in the specification. Further provided are a dye