1613289-93-2Relevant academic research and scientific papers
Combination of PhI(OAc)2 and 2-Nitropropane as the Source of Methyl Radical in Room-Temperature Metal-Free Oxidative Decarboxylation/Cyclization: Construction of 6-Methyl Phenanthridines and 1-Methyl Isoquinolines
Lu, Shi-Chao,Li, Hong-Shuang,Gong, Ya-Ling,Zhang, Shi-Peng,Zhang, Ji-Guo,Xu, Shu
, p. 15415 - 15425 (2019/01/03)
A room-temperature metal-free method for generating highly unstable methyl radical was realized from the combination of PhI(OAc)2 and 2-nitropropane, which provides an efficient approach to methylated phenanthridines and isoquinolines. The strategy was also extended to the generation of other alkyl radicals and a concise synthesis of Roxadustat.
The benzoyl peroxide-promoted functionalization of simple alkanes with 2-aryl phenyl isonitrile
Sha, Wanxing,Yu, Jin-Tao,Jiang, Yan,Yang, Haitao,Cheng, Jiang
supporting information, p. 9179 - 9181 (2014/08/05)
The benzoyl peroxide (BPO)-promoted phenanthridinylation of simple alkanes with isonitrile is developed via C(sp3)-H and C(sp2)-H bond cleavage. This procedure is featured by dual C-C bond formation proceeding with the addition of an
A free radical cascade cyclization of isocyanides with simple alkanes and alcohols
Li, Zejiang,Fan, Fenghua,Yang, Jie,Liu, Zhong-Quan
supporting information, p. 3396 - 3399 (2014/07/08)
A copper-catalyzed free-radical cascade cyclization of isocyanides with simple alkanes and alcohols was developed, which allowed convenient access to various alkyl-substituted phenanthridines.
