1613317-24-0

Basic information

• Product Name: 2-cyclohexyl-N-[7-(4-phenylthiazol-2-yl)quinolin-2-yl]succinamic acid
• Synonyms: 2-cyclohexyl-N-[7-(4-phenylthiazol-2-yl)quinolin-2-yl]succinamic acid
• CAS NO: 1613317-24-0
• Molecular Weight: 485.607
• Mol File: 1613317-24-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-cyclohexyl-N-[7-(4-phenylthiazol-2-yl)quinolin-2-yl]succinamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexyl-N-[7-(4-phenylthiazol-2-yl)quinolin-2-yl]succinamic acid(1613317-24-0)
• EPA Substance Registry System: 2-cyclohexyl-N-[7-(4-phenylthiazol-2-yl)quinolin-2-yl]succinamic acid(1613317-24-0)

Safety Data

• Hazardous Substances Data: 1613317-24-0(Hazardous Substances Data)

Upstream product

• 1489-63-0 2-cyclohexylsuccinic acid 
• 1613317-41-1 7-(4-phenylthiazol-2-yl)quinolin-2-ylamine 
• 5962-96-9 2-Cyclohexylbutandisaeure-anhydrid 
• 1613317-40-0 2-chloro-7-(4-phenylthiazol-2-yl)quinoline 
• 1613317-39-7 7-(4-phenylthiazol-2-yl)-1H-quinolin-2-one 
• 99465-10-8 7-bromo-1,2-dihydroquinolin-2-one 
• 1219130-54-7 7-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-quinolin-2-one 

Relevant articles and documents

SUBSTITUTED THIAZOLE COMPOUNDS

The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are LMP7 inhibitors and may be useful in treating associated inflammatory diseases and disorders such as, for example, rheumatoid arthritis, lupus and irritable bowel disease.