1613414-01-9

Upstream product

• 15174-69-3 4-hydroxy-3-methyl-benzaldehyde 
• 71-43-2 benzene 
• 586-38-9 3-Methoxybenzoic acid 
• 1613413-98-1 (S)-methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride 
• 1613413-97-0 (S)-methyl 4-((3-((((tert-butoxy)carbonyl)amino)(phenyl)methyl)phenoxy)methyl)benzoate 
• 1416070-91-1 (S)-tert-butyl ((3-hydroxyphenyl)(phenyl)methyl)carbamate 
• 1416069-62-9 (S)-tert-butyl ((3-hydroxyphenyl)(phenyl)methyl)carbamate 
• 1613413-99-2 Methyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)-phenoxy) methyl)benzoate 
• 1416069-97-0 (S)-Methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride 
• 1416069-96-9 (S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate 
• 1613414-00-8 4-((3-((S)-phenyl(((((R)-quinuclidin-3-yl)oxy)carbonyl)amino)methyl)phenoxy)methyl)benzoic acid 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 1416070-05-7 3-(Amino(phenyl)methyl)phenol hydrochloride 
• 1416069-95-8 N-((3-hydroxyphenyl)(phenyl)methyl)formamide 

Downstream Products

• 1613593-47-7 2-(4-((((R)-2-Hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-2-methylphenoxy)ethyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate 
• 1613604-26-4 4-(2-(((R)-2-Hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)-amino)ethyl)benzyl 3-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)-methyl)phenoxy)methyl)benzoate 
• 1613607-24-1 3-((((R)-2-Hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)benzyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate 
• 1613414-02-0 2-(4-((((R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-2-methylphenoxy)ethyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoate formate 

Relevant academic research and scientific papers

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

The present invention relates to compounds acting both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists, to processes for their preparation, to compositions comprising them, to therapeutic uses and combinations with other pharmaceutical active ingredients.

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

Compounds of formula (I) described herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.