1613414-80-4

Upstream product

• 1613414-65-5 methyl 1-methyl-5-(((methylsulfonyl)oxy)methyl)-1H-pyrazole-3-carboxylate 
• 1613414-67-7 Methyl 1-methyl-5-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl) phenoxy)methyl)-1H-pyrazole-3-carboxylate 
• 1208081-63-3 methyl 5-(hydroxymethyl)-1-methyl-1H-pyrazole-3-carboxylate 
• 1613414-93-9 5-((3-((S)-phenyl(((R)-quinuclidin-3-yloxy)carbonylamino)methyl)phenoxy) methyl)furan-2-carboxylic acid formate 
• 6136-67-0 3-methoxybenzophenone 
• 13020-57-0 3-hydroxybenzophenone 
• 1416069-95-8 N-((3-hydroxyphenyl)(phenyl)methyl)formamide 
• 1416070-05-7 3-(Amino(phenyl)methyl)phenol hydrochloride 
• 1416069-96-9 (S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate 
• 1416069-97-0 (S)-Methyl 4-((3-(amino(phenyl)methyl)phenoxy)methyl)benzoate hydrochloride 
• 1613413-99-2 Methyl 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)-phenoxy) methyl)benzoate 

Downstream Products

• 1613414-95-1 4-(((R)-2-(8-(Benzyloxy)-2-oxo-1,2-dihydroquinolin-5-yl)-2-((tert-butyldimethylsilyl)oxy)ethyl)((tert-butoxy)carbonyl)amino)butyl 5-((3-((S)-phenyl(((R)-quinuclidin-3-yloxy)carbonylamino)methyl)phenoxy)methyl)furan-2-carboxylate 
• 1613414-92-8 5-((3-((S)-phenyl(((R)-quinuclidin-3-yloxy)carbonylamino)methyl)phenoxy)-methyl)furan-2-carboxylic acid hydrochloride 

Relevant academic research and scientific papers

BENZHYDRYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES

The invention relates to novel compounds of formula (I) having a benzhydryl structure which are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

Compounds of formula (I) defined herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

Compounds of formula (I) described herein act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for the prevention and/or treatment of broncho-obstructive or inflammatory diseases.