1613439-40-9

Upstream product

• 22042-73-5 4-(2-hydroxy-ethoxy)-benzaldehyde 
• 13610-02-1 1-phenoxy-2-propyne 
• 1613439-37-4 4-[2-(cholest-5-en-3β-yloxy)ethoxy]benzaldehyde oxime 
• 1613439-34-1 4-[2-(cholest-5-en-3β-yloxy)ethoxy]benzaldehyde 
• 57-88-5 cholesterol 

Relevant academic research and scientific papers

C-3β-tethered functional cholesterol conjugates by nitrile oxide alkyne cycloaddition (NOAC)

Covalent cholesterol conjugates have been prepared by isoxazole-generating [3+2] nitrile oxide alkyne cycloaddition (NOAC) chemistry. Steroidal building blocks functionalised with either an alkyne or a nitrile oxide precursor were evaluated. The reaction has been demonstrated for the tethering to cholesterol of groups capable of bioreporting, and for the formation of cholesterol- biomolecule conjugates. Nitrile oxide alkyne cycloaddition (NOAC) chemistry - a tool for attaching cholesterol to biomolecules or groups capable of bioreporting. Copyright