1613459-75-8

Upstream product

• 1613459-64-5 2-(4-chlorophenyl)-6-(diethoxymethyl)-3-fluoro-N-tritylpyridin-4-amine 
• 104-86-9 4-chlorobenzylamine 
• 123-91-1 1,4-dioxane 
• 1613459-98-5 N-tert-butyl-2-(4-chlorophenyl)-6-(diethoxymethyl)-3-fluoropyridin-4-amine 

Downstream Products

• 496851-93-5 4-amino-3-chloro-6-(4-chlorophenyl)-5-fluoropicolinic acid 
• 1613459-85-0 4-Amino-3-chloro-6-(4-chlorophenyl)-5-fluoropyridine-2-carbaldehyde 

Relevant academic research and scientific papers

Synthesis of Novel Fluoropicolinate Herbicides by Cascade Cyclization of Fluoroalkyl Alkynylimines

The cascade cyclization of fluoroalkyl alkynylimines with primary amines has been modified to allow the synthesis of 4-amino-5-fluoropicolinates. Use of N-trityl and acetal protecting groups in the cyclization precursor led to 5-fluoropyridines that were

PROCESSES FOR THE PREPARATION OF 4-AMINO-3-HALO-6-(SUBSTITUTED)PICOLINATES AND 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES

4-Amino-3-chloro-6-(substituted)picolinates are prepared from difluoroacetic acid or trifluoroacetic acid, tritylamine or t-butylamine as a protecting group, a 3,3-dialkoxyprop-1-yne and a substituted methylene amine by a series of steps.