1613466-82-2Relevant academic research and scientific papers
Novel one-pot synthesis of diverse γ,δ-unsaturated β-ketoesters by thermal cascade reactions of diazodicarbonyl compounds and enol ethers: Transformation into substituted 3,5-diketoesters
Pandit, Rameshwar Prasad,Lee, Yong Rok
supporting information, p. 4407 - 4411 (2014/06/23)
Sequential Wolff rearrangement of α-diazo-β-ketoesters followed by trapping of the ketene intermediates with enol ethers generated a variety of γ,δ-unsaturated β-ketoesters. This method involves a novel thermal cascade reaction and allows the synthesis of γ,δ-unsaturated β-ketoesters with trans-stereochemistry under catalyst-free conditions. The synthesized compounds were further transformed into novel 3,5-diketoesters, which were used for the synthesis of naturally occurring 2-pyrone and 1-naphthoic acid ester. the Partner Organisations 2014.
