161361-83-7Relevant academic research and scientific papers
Design, synthesis, and evaluation of CC-1065 and duocarmycin analogs incorporating the 2,3,10,10a-tetrahydro-1H-cyclopropa[d]benzo[f]quinol-5-one (CBQ) alkylation subunit: Identification and structural origin of subtle stereoelectronic features that gover
Boger, Dale L.,Mesini, Philippe
, p. 11335 - 11348 (2007/10/02)
The synthesis of 2,3,10,10a-tetrahydro-1H-cyclopropa[d]benzo[f]quinol-5-one (10, CBQ), containing a deep-seated structural variation in the CC-1065 and duocarmycin alkylation subunits with incorporation of a ring expanded fused six- versus five-membered r
