78839-75-5

Basic information

• Product Name: N-(TERT-BUTOXYCARBONYL)-2-BROMOANILINE
• Synonyms: N-Boc 2-broMoaniline;tert-butyl (2-broMophenyl)carbaMate;2-Bromo-N-(tert-butoxycarbonyl) aniline;N-(tert-Butoxycarbonyl)-2-bromoaniline 97%;tert-Butyl (2-bromophenyl)
• CAS NO: 78839-75-5
• Molecular Formula: C₁₁H₁₄BrNO₂
• Molecular Weight: 272.14
• Product Categories: Nitrogen Compounds;Organic Building Blocks;Protected Amines;amine|alkyl bromide| carboxylic ester
• Mol File: 78839-75-5.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 110 °C0.3 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.342 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00408mmHg at 25°C
• Refractive Index: n20/D 1.54(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: N-(TERT-BUTOXYCARBONYL)-2-BROMOANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(TERT-BUTOXYCARBONYL)-2-BROMOANILINE(78839-75-5)
• EPA Substance Registry System: N-(TERT-BUTOXYCARBONYL)-2-BROMOANILINE(78839-75-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 78839-75-5(Hazardous Substances Data)

Usage

Uses

N-(tert-Butoxycarbonyl)-2-bromoaniline may be used in the synthesis of N-boc-protected o-aryl anilines, which undergoes coupling reaction with bromoacetylenes to form the corresponding arene?ynamides.

General Description

N-(tert-Butoxycarbonyl)-2-bromoaniline, also known as tert-butyl-N-(2-bromophenyl)carbamate, is an N-Boc-protected o-bromoaniline.1 It reacts with ethyl perfluorooctanoate in the presence of tert-butyllithium to form the corresponding 1-hydroxy-1H-perfluorooctyl compound.

InChI:InChI=1/C11H14BrNO2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8(9)12/h4-7H,1-3H3,(H,13,14)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 615-36-1 2-bromoaniline 
• 50625-50-8 2-bromo-benzoyl azide 
• 75-65-0 tert-butyl alcohol 
• 880384-47-4 di-tert-butyl (2-bromophenyl)carbamate 
• 3422-01-3 tert-butyl phenylcarbamate 
• 34619-03-9 tert-butyldicarbonate 
• 36016-38-3 tert-Butyl N-hydroxycarbamate 

Downstream Products

• 3422-01-3 tert-butyl phenylcarbamate 
• 78839-79-9 (4aS,9aR)-4a-Hydroxy-1,2,3,4,4a,9a-hexahydro-carbazole-9-carboxylic acid tert-butyl ester 
• 161361-83-7 N-allyl-N-(t-butoxycarbonyl)-2-bromoaniline 
• 187099-49-6 2-((trimethylsilyl)ethynyl)phenylaminocarboxylic acid tert-butyl ester 
• 159624-15-4 tert-butyl N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate 
• 442850-92-2 (2-vinylphenyl)carbamic acid tert-butyl ester 
• 700862-62-0 diethyl (E)-2-{2-[(tert-butoxycarbonyl)amino]phenyl}ethenephosphonate 
• 935742-36-2 (2-bromo-phenyl)-(2-methyl-allyl)-carbamic acid tert-butyl ester 
• 955123-21-4 [2-(1H-indol-5-yl)-phenyl]-carbamic acid tert-butyl ester 
• 909297-32-1 trans-(2-styrylphenyl)carbamic acid tert-butyl ester 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 912918-24-2 C₁₅H₂₃NO₂ 
• 912918-22-0 N-(2-perfluorooctanoylphenyl)carbamate 
• 912918-25-3 C₁₄H₆F₁₅NO 

Relevant articles and documents

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