161366-59-2

Upstream product

• 16652-71-4 benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride 
• 37553-65-4 N-tert-butoxycarbonyl-N-methyl-D-phenylalanine 
• 37787-77-2 Boc-L-proline benzyl ester 

Downstream Products

• 757912-61-1 N-Me-D-Phe-Pro-OCH₂Ph 
• 138775-40-3 H-L-(N^δ-Boc)Orn-D-(N-Me)Phe-L-Pro-OCH2Ph 
• 127819-88-9 cyclo-(D-Phe-Ile-D-Pip-Pip-D-(N-Me)Phe-Pro) 
• 127819-91-4 cyclo- 
• 138774-90-0 D-Phe-Ile-D-Pip-L-Pip-N-Me-D-Phe-Pro-NH-NH₂ 
• 127819-99-2 C₄₄H₆₀N₆O₇ 
• 127819-92-5 cyclo- 
• 114669-39-5 L-365,209 
• 138775-41-4 Ile-D-Δ-Piz-(N^δ-Boc)Orn-N-Me-D-Phe-Pro-OCH2Ph 
• 138774-82-0 D-Phe-Ile-D-Pip-L-Pip-N-Me-D-Phe-Pro-OCH₂-Ph 

Relevant academic research and scientific papers

Total Synthesis of L-156,373 and an oxoPiz Analogue via a Submonomer Approach

The first chemical synthesis of L-156,373 (1), a potent oxytocin receptor antagonist isolated from Streptomyces silvensis, is reported. Assembly of the unusual d-Piz-l-Piz dipeptide subunit was achieved through a sequential electrophilic amination-acylati