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1614-59-1

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1614-59-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1614-59-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1614-59:
(6*1)+(5*6)+(4*1)+(3*4)+(2*5)+(1*9)=71
71 % 10 = 1
So 1614-59-1 is a valid CAS Registry Number.

1614-59-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,5-bis[2-(diethylamino)ethylamino]anthracene-9,10-dione

1.2 Other means of identification

Product number -
Other names 1,5-bis-{[2-(diethylamino)ethyl]amino}anthracene-9,10-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1614-59-1 SDS

1614-59-1Downstream Products

1614-59-1Relevant articles and documents

Comparative Computer Graphics and Solution Studies of the DNA Interaction of Substituted Anthraquinones Based on Doxorubicin and Mitoxantrone

Islam, Suhail A.,Neidle, Stephen,Gandecha, Bijukumar M.,Partridge, Malcolm,Patterson, Laurence H.,Brown, Jeffrey R.

, p. 857 - 864 (1985)

1-amino>- and 1,4-, 1,5-, and 1,8-bisamino>anthraquinones are shown to intercalate into DNA.Computer graphics modelling of their intercalation into the self-complementary deoxydinucleoside d(CpG) showed differences in binding properties.While the 1-substituted compound can bind from euther groove, the 1,8-disubstituted compound binds with both substituents in the major groove.In the-low energy state of the complex with the 1,5-disubstituted compound, this ligand "straddles" the site with a substituent in each groove-to do this, the compound must bind to a non-base-paired region, so inducing base pairing.The 1,4-compound binds from the major groove; "straddling" is also possible if full minimization of deoxydinucleoside geometry is performed.The differences in binding mode and interaction energies are reflected in the affinities of interaction (1,5- > 1,4- >> 1,8- > 1-); also the antiproliferative effects in vitro are in general agreement with this ranking.

Synthesis of aminoanthraquinone derivatives and their in vitro evaluation as potential anti-cancer drugs

Katzhendler,Gean,Bar-Ad,Tashma,Ben-Shoshan,Ringel,Bachrach,Ramu

, p. 23 - 30 (2007/10/02)

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