1614220-48-2Relevant academic research and scientific papers
A new approach for the synthesis of N-sulfonyl hydantoins
Rmedi, Hamdi,Baklouti, Ahmed
, p. 3585 - 3587 (2014/06/23)
Two methods are described for the synthesis of a new series of hydantoins using the same reagents. The best process is based on the addition of N-aryloxy(alkoxy)sulfonyl isocyanates to an equimolar mixture of bromoamides and triethylamine dissolved in anhydrous acetone. This reaction is violent and provides the urea salts in situ which are transformed into the corresponding substituted hydantoins.
