161452-12-6Relevant articles and documents
Intermolecular 1,2-Difunctionalization of Alkenes Enabled by Fluoroamide-Directed Remote Benzyl C(sp3)-H Functionalization
Li, Jin-Heng,Li, Yang,Lu, Xin,Ouyang, Xuan-Hui,Song, Ren-Jie,Sun, Qing,Xiong, Zhi-Qiang,Zhong, Long-Jin
supporting information, (2022/01/08)
A copper-catalyzed remote benzylic C-H functionalization strategy enabling 1,2-difunctionalization of alkenes with 2-methylbenzeneamides and nucleophiles, including alcohols, indoles, pyrroles, and the intrinsic amino groups, is reported, which is charact
Copper-Catalyzed, N-Directed Csp3-H Trifluoromethylthiolation (-SCF3) and Trifluoromethylselenation (-SeCF3)
Modak, Atanu,Pinter, Emily N.,Cook, Silas P.
supporting information, p. 18405 - 18410 (2019/11/19)
A direct and versatile copper-catalyzed trifluoromethylthiolation and trifluoromethylselenation of primary, secondary, and tertiary aliphatic C-H bonds was developed. The reaction provides direct access to molecules containing these emerging moieties in the presence of a wide range of common functional groups and in complex molecular environments.
Antiproliferative Properties of Polyamine Analogues: A Structure-Activity Study
Bergeron, Raymond J.,McManis, James S.,Liu, Charles Z.,Feng, Yang,Weimar, William R.,et al.
, p. 3464 - 3476 (2007/10/02)
A basis set of polyamine analogues was designed and synthesized.These compounds were used to initiate a systematic investigation of the role of chain length, terminal nitrogen alkyl group size, and symmetry of the methylene backbone in the antineoplastic
