16154-18-0Relevant academic research and scientific papers
Prolinamide/PPTS-catalyzed Hajos-Parrish annulation: Efficient approach to the tricyclic core of cylindricine-type alkaloids
Zhang, Xiao-Ming,Wang, Min,Tu, Yong-Qiang,Fan, Chun-An,Jiang, Yi-Jun,Zhang, Shu-Yu,Zhang, Fu-Min
scheme or table, p. 2831 - 2835 (2009/05/07)
A series of Wieland-Miescher ketone analogues bearing highly functionalized substituents are efficiently constructed in high enantioselectivities and good yields using catalytic amounts of prolinamide and PPTS. We have successfully utilized this reaction as a key step to synthesize the tricyclic core of cylindricine type alkaloids. Georg Thieme Verlag Stuttgart.
