161562-06-7

Upstream product

• 161561-98-4 (3S)-methanesulfonic acid 4-cyano-3-(N,N-dibenzylamino)butyl ester 
• 137428-32-1 (2S)-2-[bis(phenylmethyl)amino]-1,4-butanediol 
• 161561-97-3 Methanesulfonic acid (S)-2-dibenzylamino-4-methanesulfonyloxy-butyl ester 

Downstream Products

• 213134-90-8 (4S)-1-benzyl-4-(N,N-dibenzylamino)piperidin-2-one 
• 213134-97-5 (3R,4S)-1-benzyl-4-(N,N-dibenzylamino)-3-methylpiperidin-2-one 
• 213134-91-9 (4S)-4-(N,N-dibenzylamino-2-oxopiperidin-1-yl)acetic acid ethyl ester 
• 213134-89-5 (4S)-4-(N,N-dibenzylamino)-2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 213134-94-2 (2S,4S)-4-[[[1-benzyloxycarbonyl-2-pyrrolidinyl]carbonyl]amino](2-oxopiperidin-1-yl)acetamide 
• 213134-93-1 (2S,4S)-4-[[[1-benzyloxycarbonylpyrrolidine-2-carbonyl]amino]piperidin-1-yl]acetic acid ethyl ester 
• 213134-88-4 (4S)-4-(N,N-dibenzylamino)piperidin-2-one 
• 213134-87-3 (3S)-5-amino-3-(N,N-dibenzylamino)pentanenitrile 

Relevant academic research and scientific papers

Homo-Freidinger lactams: Stereoselective synthesis of 4-aminopiperidin-2-one derivatives from aspartic acid

Starting from aspartic acid a stereoselective synthesis of enantiomerically pure 4-aminopiperidin-2-ones which can serve as conformationally restrained β-amino acid equivalents in peptidomimetics is described. The synthesis is based on the regioselective

2-Dibenzylaminobutane-1,4-diol: A Versatile Intermediate for a Chirospecific β-amino Acid Synthesis

Starting from the chiral building block 1, which is readily available from natural aspartic acid, a concise and versatile synthesis of optically active β-amino acids including β-proline derivatives is reported.Regioselective transformations of the 1,4-bis-electrophile 2 are facilitated by an anchimeric participation.