1615729-97-9

Upstream product

• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 1615729-70-8 tert-butyl 4-(4-(4-fluorophenyl)-1H-imidazol-1-yl)piperidine-1-carboxylate 
• 1615729-72-0 tert-butyl 4-(5-bromo-4-(4-fluorophenyl)-1H-imidazol-1-yl)piperidine-1-carboxylate 
• 887625-09-4 6-chloroimidazo[1,2-b]pyridazine-2-amine 
• 1615729-95-7 tert-butyl 4-(5-(2-acetamidoimidazo[1,2-b]pyridazin-6-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)piperidine-1-carboxylate 
• 947248-51-3 N-(6-chloroimidazo[1,2-b]pyridazin-2-yl)acetamide 
• 1162680-90-1 N-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazin-2-yl)acetamide 

Downstream Products

• 1615720-74-5 N-(6-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)isonicotinamide 
• 1615720-75-6 N-(6-(4-(4-fluorophenyl)-1-(1-methylpiperidin-4-yl)-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)isonicotinamide 
• 1615720-80-3 (R)-N-(6-(4-(4-fluorophenyl)-1-(1-(3,3,3-trifluoro-2-hydroxypropyl)piperidin-4-yl)-1H-imidazol-5-yl)imidazo[1,2-b]pyridazin-2-yl)isonicotinamide 
• 1615729-99-1 tert-butyl 4-(5-(2-aminoimidazo[1,2-b]pyridazin-6-yl)-4-(4-fluorophenyl)-1H-imidazol-1-yl)piperidine-1-carboxylate 

Relevant academic research and scientific papers

NOVEL SUBSTITUTED IMIDAZOLES AS CASEIN KINASE 1 δ/ε INHIBITORS

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The compounds of Formula (I) inhibit protein kinase activity thereby making them useful as anticancer agents.