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161596-62-9

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161596-62-9 Usage

Description

(+/-)-TRANS-AZETIDINE-2,4-DICARBOXYLIC ACID is a white to off-white powder with chemical properties that make it a potentially useful compound in various applications.

Uses

Used in Pharmaceutical Industry:
(+/-)-TRANS-AZETIDINE-2,4-DICARBOXYLIC ACID is used as a compound for inhibiting forskolin-stimulated cAMP accumulation by 33% in Chinese hamster ovary (CHO) cells expressing human mGlu2 receptors. This property suggests its potential use in the development of drugs targeting mGlu2 receptors, which are involved in various neurological and psychiatric disorders.

Biological Activity

Group I selective metabotropic glutamate receptor agonist. More potent at mGlu 5a than mGlu 1a in LLC-PKI cells and induces calcium release in CA3 pyramidal cells in vitro .

Check Digit Verification of cas no

The CAS Registry Mumber 161596-62-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,1,5,9 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 161596-62:
(8*1)+(7*6)+(6*1)+(5*5)+(4*9)+(3*6)+(2*6)+(1*2)=149
149 % 10 = 9
So 161596-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H7NO4/c7-4(8)2-1-3(6-2)5(9)10/h2-3,6H,1H2,(H,7,8)(H,9,10)/p-1/t2-,3-/m0/s1

161596-62-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,4S)-azetidine-2,4-dicarboxylic acid

1.2 Other means of identification

Product number -
Other names Azetidine-2,4-dicarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:161596-62-9 SDS

161596-62-9Downstream Products

161596-62-9Relevant articles and documents

Synthesis of optically active azetidine-2,4-dicarboxylic acid and related chiral auxiliaries for asymmetric synthesis

Hoshino, Jun'ichi,Hiraoka, Junko,Hata, Yasuo,Sawada, Seiji,Yamamoto, Yukio

, p. 693 - 698 (2007/10/02)

(S)-1-Phenylethylamine has been used as a chiral auxiliary as well as a nitrogen atom donor in the synthesis of an enantiomeric pair of azetidine-2,4-dicarboxylic acids, the absolute configuration of one of which has been assigned on the basis of the X-ra

Azetidine derivatives to treat memory and learning disorders

-

, (2008/06/13)

This invention relates to novel azetidines and derivatives thereof, as well as to pharmaceutical compositions and methods of treating memory and learning disorders. Another aspect of the invention relates to a method of utilizing the compounds and composi

Azetidine derivatives, compositions and methods of treating

-

, (2008/06/13)

This invention relates to novel azetidines and derivative thereof, as well as to pharmaceutical compositions and methods of treating memory and learning disorders. Another aspect of the invention relates to a method of utilizing the compounds and compositions as biological tools and materials for characterizing excitatory amino acid receptor systems. A further aspect of the invention relates to a method of treating PCP toxicity and abuse.

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