1616059-77-8

Basic information

• Product Name: 1-methyl-6-(3-(oxiran-2-ylmethoxy)phenyl)-1H-benzo[d]imidazole
• Synonyms: 1-methyl-6-(3-(oxiran-2-ylmethoxy)phenyl)-1H-benzo[d]imidazole
• CAS NO: 1616059-77-8
• Molecular Weight: 280.326
• Mol File: 1616059-77-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-methyl-6-(3-(oxiran-2-ylmethoxy)phenyl)-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-6-(3-(oxiran-2-ylmethoxy)phenyl)-1H-benzo[d]imidazole(1616059-77-8)
• EPA Substance Registry System: 1-methyl-6-(3-(oxiran-2-ylmethoxy)phenyl)-1H-benzo[d]imidazole(1616059-77-8)

Safety Data

• Hazardous Substances Data: 1616059-77-8(Hazardous Substances Data)

Upstream product

• 1616059-76-7 3-(1-methyl-1H-benzo[d]imidazol-6-yl)phenol 
• 106-89-8 epichlorohydrin 
• 1107627-01-9 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole 
• 53484-16-5 6-bromo-1-methyl-1H-benzo[d]imidazole 
• 337915-79-4 4-bromo-N²-methylbenzene-1,2-diamine 
• 321-23-3 4-bromo-2-fluoronitrobenzene 
• 302800-13-1 5-bromo-N-methyl-2-nitroaniline 

Relevant articles and documents

PRMT5 INHIBITORS AND USES THEREOF

Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof:wherein Y1 is of formula (?) or formula (y):Ring Y is a 5- to 6-membered heteroaryl ring; and V4, V5, Rx, x, y, and n are as defined herein. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.