161617-42-1Relevant articles and documents
Synthesis of 1,2,3,9-tetrahydro-7-bromo-6-hydroxy-5-methoxypyrrolo-[2,1-b]- quinazol ine: A new analog of deoxyvasicine
Ojo,Chowdhury
, p. 569 - 572 (1995)
A new deoxyvasicine analog (9) was synthesized by condensation of 2-amino-5-bromovanillin (6) with 4-aminobutyraldehyde (7) in phosphate buffer (pH 5.8) followed by hydrogenation of the resulting quinazolinium complex (8) at 65°C in presence of 5% palladium-on-barium sulfate.
As a new polyphenylenepolymethylenepolyisocyanate deriv. SGLT2 inhibitor
-
, (2016/10/09)
A compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney is disclosed. A pharmaceutical composition including the compound as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes is disclosed. A method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound is provided.