1616353-76-4Relevant academic research and scientific papers
A highly selective fluorogenic probe for the detection and: In vivo imaging of Cu/Zn superoxide dismutase
Zhang, Liyun,Er, Jun Cheng,Jiang, Hao,Li, Xin,Luo, Zhaofeng,Ramezani, Thomas,Feng, Yi,Tang, Mui Kee,Chang, Young-Tae,Vendrell, Marc
, p. 9093 - 9096 (2016)
Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.
MEGASTOKES AMINO-TRIAZOLYL-BODIPY COMPOUNDS AND APPLICATIONS TO LIVE NEURON STAINING AND HUMAN SERUM ALBUMIN FA1 DRUG SITE PROBING
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Page/Page column 9; 10; 31, (2014/07/21)
A library of novel amino-triazolyl-BODIPY compounds is described. Particular compounds of the library serve as selective fluorescent probes Human Serum Albumin (HSA) and for live primary neurons. The fluorescent probe for HSA binds uniquely and specifically to the fatty acid site 1 of HSA, and thus proves a valuable and unique probe for drugs that bind to such a site on HSA. Methods of synthesis for the library compounds are also described.
