1616562-66-3Relevant academic research and scientific papers
AgN3-Catalyzed Hydroazidation of Terminal Alkynes and Mechanistic Studies
Bi, Xihe,Cao, Shanshan,Ji, Qinghe,Li, Huaizhi,Pang, Maolin,Yuan, Haiyan,Zhang, Jingping
, p. 7083 - 7091 (2020)
The hydroazidation of alkynes is the most straightforward way to access vinyl azides-versatile building blocks in organic synthesis. We previously realized such a fundamental reaction of terminal alkynes using Ag2CO3 as a catalyst. H
General silver-catalyzed hydroazidation of terminal alkynes by combining TMS-N3 and H2O: Synthesis of vinyl azides
Liu, Zhenhua,Liao, Peiqiu,Bi, Xihe
supporting information, p. 3668 - 3671 (2014/08/05)
A general hydroazidation of unactivated alkynes using silver catalysis is reported. The reactions of diverse terminal alkynes with trimethylsilyl azide (TMS-N3) in the presence of H2O afforded the corresponding vinyl azides in good to excellent yields. This reaction has a broad substrate scope, good functional group tolerance, simple operation, and high reaction efficiency, thus providing an easy access to various functionalized vinyl azides.
